Resources
Explore comprehensive data, application notes, and posters highlighting the G4 Sequencing Platform’s performance and capabilities.
Applications
RNA Sequencing
RNA sequencing (RNA-Seq) is used to assess differential gene expression profiles, detect novel transcripts, and characterize new splice variants or cell types. Explore how the reimagined chemistry and advanced engineering of the G4 can improve your RNA sequencing.
Single Cell RNA Sequencing
Single cell RNA sequencing (scRNA-Seq) has revolutionized basic and translational research in immunology, developmental biology and cancer by enabling the resolution of distinct cell populations within heterogeneous samples. Explore how the G4 can seamlessly integrate into your scRNA-Seq workflow and accelerate your results without sacrificing accuracy.
Whole Exome Sequencing
Whole exome sequencing (WES) is a next-generation sequencing method used to discover and assess genetic variations linked to rare or complex diseases. Learn how the G4 provides excellent variant-calling accuracy and unmatched speed and versatility to labs performing WES.
Whole Genome Sequencing
Whole genome sequencing (WGS) is the process for analyzing the complete genetic makeup of an organism. Learn more about the suitability of the G4 for human whole genome sequencing in the WGS technical report.
Videos
Posters & Publications
AMP 2022
Performance Assessment of the G4 Sequencing Platform for Rapid and Flexible Next Generation Sequencing
by Singular Genomics (Kenneth Gouin III et al.)
AMP 2022
Ring-Seq: A Novel Technology for Multiplex PCR Based Detection of Gene Fusions with Novel Partners and Breakpoints from Highly Degraded Material
by Singular Genomics (Richard Que et al.)
ASHG 2022
Max Read: A Novel High-Throughput Short-Read Format for the G4™ Sequencing Platform
by Singular Genomics (Niek van Wietmarschen et al.)
ASHG 2022
Single Cell RNA Sequencing with the G4™ Sequencing Platform
by Singular Genomics (Kenneth Gouin III et al.)
AGBT 2022
Singular Genomics’ G4 Platform Technology Assessment
by TGEN (Candice L. Wilke et al.)
AGBT 2022
Training and Validation of an Accelerated DeepVariant Model for Germline Exome Analysis on the G4
by Singular Genomics (Kenneth Gouin III et al.)
AMP 2022
Rapid Targeted Germline and Somatic Variant Detection Using the G4™ Sequencing Platform
by Singular Genomics (Kenneth Gouin III et al.)
ASHG 2022
Rapid Whole Genome and Whole Exome Variant Detection Using a Novel Fluorescently Labeled Reversible Terminated Nucleotide Sequencing System and GPU-based Accelerated Analysis
by Singular Genomics (Kenneth Gouin III et al.)
ASHG 2022
HD-Seq: A Novel Method for High Accuracy Sequencing
by Singular Genomics (Sabrina Shore et al.)
AGBT 2022
Bacterial Whole Genome Assembly and Microbial Community Analysis with the G4
by JGI (Christopher G. Daum et al.)
AGBT 2022
Evaluation of the Singular Genomics G4 Sequencing Platform with Resolution ctDx Assays on Cell-Free DNA
by Resolution Biosciences (Carolyn Hutcheon et al.)
bioRxiv, 2022
XR-Seq: Reconstruction of Full-Length scFv Libraries with the Extended Range Targeted Sequencing Method
(Christopher Wei et al.)
Innovation with Intention
Featuring novel, high-performance chemistry and advanced engineering, the G4 Sequencing Platform has been optimized to deliver speed, power, unprecedented flexibility, and accuracy.