Efficient and Cost-Effective Sequencing on the G4

The G4 is designed for practical cost savings. Laboratories achieve routine cost savings through streamlined lab operations, efficient consumable use, and capex reduction.

Adaptive Sequencing Capacity

Eliminate batching bottlenecks and sequence cost effectively on-demand across 1-4 flow cells and 8 run sizes1.

Streamlined Lab Operations

Simplified sequencing project management with 16 individual lanes per run.

Capex
Reduction

Expanded capacity to process more samples per year on a single system. One G4 has the sequencing power of ~2.5 leading benchtop instruments.

Sample Cost Comparison Tool

Compare flow cell, cost, and run time efficiency against the NextSeq 2000 for your application.

Overview

Click on the flow cell configurations for more read details. Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000.

Flow Cell Configuration

  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • Unused flow cell space
  • Used flow cell space

G4

G4
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.

G4

G4
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.

1 F2 Flow Cell
200M Reads

G4

G4
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.

1 F3 Flow Cell
400M Reads

G4

G4
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.

1 F2 + 1 F3 Flow Cell
600M Reads

G4

G4
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.

2 F3 Flow Cells
800M Reads

G4

G4
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.

3 F3 Flow Cells
1.2B Reads

G4

G4
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.

4 F3 Flow Cells
1.6B Reads

  • P1
  • P2
  • P3

Reads
Delivered

NextSeq 2000

G4
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

NextSeq 2000

G4
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

100M reads

NextSeq 2000

G4
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

400M reads

NextSeq 2000

G4
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

1.2B reads

Shotgun Metagenomics

Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.

  • Unused flow cell space
  • Used flow cell space

G4

$100/sample

NextSeq 2000

$454/sample
Small Genomes
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

Transcriptomes

Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.

  • Unused flow cell space
  • Used flow cell space

G4

$110/sample

NextSeq 2000

$342/sample
8 Transcriptomes
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

Exomes

Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.

  • Unused flow cell space
  • Used flow cell space

G4

$110/sample

NextSeq 2000

$342/sample
8 Exomes
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

Small RNA

Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.

  • Unused flow cell space
  • Used flow cell space

G4

$75/sample

NextSeq 2000

$156/sample
8 Small RNA
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

Single Cell

Select your application and number of samples to compare flow cell, cost, and run time efficiency against the leading benchtop sequencer. Click on the flow cell configurations for more information.

  • Unused flow cell space
  • Used flow cell space

G4

$200/sample

NextSeq 2000

$833/sample
4 single cell
Flow Cell Configuration (Run Sizes)?G4 is capable of running 1-4 flow cells and 6 different configurations. See configuration selector for more details.
Flow Cell Configuration (Run Sizes)?NextSeq 2000 is capable of running 1 flow cell at a time, with three different flow cell options.

G4 Pricing

Learn More About Additional Savings Due to Operational Efficiencies Not Seen on Other Platforms

Let our experts model out the additional layers of cost savings due more efficient sequencing based on your specific lab operation and see how the G4 can save your lab hundreds of thousands of dollars per year.

Request a Consultation

Discover G4

Featuring novel, high-performance chemistry and advanced engineering, the G4 Sequencing Platform has been optimized to deliver speed, power, unprecedented flexibility, and accuracy.

EXPLORE
1F2 and F3 Flow cell run combinations and resulting 8 run sizes are in development and not currently available to customers; please contact your sales representative for more information

Request A Quote

Please provide your information and a member of the Singular Genomics team will be in contact with additional G4 details and pricing.

Request A Consultation

Please provide your information and a member of the Singular Genomics team will be in contact to set up a consultation.

Drew Spaventa

Drew founded Singular Genomics in 2016 serving as the CEO and Chairman. Drew is a serial entrepreneur and venture investor in the biotech industry and has been involved in the founding of several successful companies. Prior to Singular Genomics, Drew founded Truvian Sciences, a low volume blood testing technology aimed at making routine blood tests easier, less invasive, and more affordable. Drew was also involved in the founding of Aspen Neurosciences where he co-led the seed financing and helped assemble a world-class team to combat Parkinson’s Disease using a patient’s own stem cells. Drew was also a seed investor and held an operating role in Edico Genome which sold to Illumina in 2018.

Drew received an MBA from the Rady School of Management at the University of California, San Diego and a BA in Political Science and International Relations from the University of California, San Diego.

Drew Spaventa

Max Reads Application Note