Fast, Cost-Effective Single Cell RNA Sequencing

There is a growing desire to answer questions about the genome at the level of the individual cell. Single cell technologies promise to make significant impact on research and clinical studies; however, complimentary high-throughput sequencing for these studies requires large capital expenditure and expensive consumables. The G4™ Sequencing Platform addresses these challenges and enables researchers to generate low-cost, accurate scRNA-seq results with more flexibility and speed than any other sequencer on the market.

Delivering Power and Flexibility for Single Cell Sequencing Labs

The G4 features proprietary 4-color Rapid SBS chemistry and advanced engineering, designed to provide labs with unmatched operational efficiency and industry-leading run times. The G4 integrates seamlessly into existing NGS workflows and is well suited for single cell sequencing labs.

Key capabilities:

Single-day turnaround times
Highly accurate data
1 – 4 flow cell, 4 – 16 lane run flexibility
Up to 3.2 B reads per run

Highly Accurate Single Cell RNA Sequencing on the G4

Highly-accurate single cell data comparable to the NextSeq 2000
Rapid and cost-efficient sequencing of single cell RNA sequencing (scRNA-seq) libraries
Seamless compatibility of the G4 Sequencing Platform with 10x library preparation workflows and bioinformatics pipelines

Introducing Max Read™ Sequencing Kits

High throughput, low-cost single cell sequencing.
Up to 3.2 billion reads per run at $1 per million reads.

G4 Specifications for Single Cell Sequencing

	F2 Flow Cell	F3 Flow Cell	Max Reads²
Reads Delivered / Flow Cell	200 M	400 M	800 M
Reads Delivered / Run	800 M	1,600 M	3,200 M
# Samples / Flow Cell¹	1	2	4
# Samples / Run¹	4	8	16
Price/M Read	$3.0	$1.8	$1.0
Run Time	~15 hours	~15 hours	~24 hours
Quality (Q30)	80-90%	80-90%	80-90%

The G4 can process up to 4 flow cells in parallel. Number of reads and sequencing output shown is per flow cell.
¹Assumes 28×91 read configuration, 10,000 cells/sample and 20,000 reads/cell
²Max Read kits are only compatible with 10x samples and allow for 1 sample per lane. Max Reads cannot be run at the same time as F2 or F3 flow cells

G4 Plug-and-Play Capability

We have partnered with industry-leading library preparation providers and bioinformatic pipelines to ensure the G4 Sequencing Platform seamlessly integrates into existing NGS workflows.