G4 Workflow

The G4 Sequencing Platform is the a plug-and-play solution that seamlessly integrates into existing NGS workflows. 

Prepare

  • With the integration of industry-leading library prep kits and Singular’s custom adapters and indices, G4 can slot into existing NGS workflows. 

Sequence

  • Intuitive user interface and easy-to-use reagents empower anyone to load and run a wide variety of applications on G4.

Analyze

  • G4 seamlessly connects to leading cloud storage providers and generates demultiplexed FASTQ files that can can be easily integrated into existing bioinformatic pipelines.

Library Prep Partners

Integrating the Roche KAPA® DNA and RNA Library Preparation Kits with G4.

Integrating the 10x Genomics Chromium Single Cell platform with G4.

Integrating NEBNext® DNA and RNA Library Preparation Kits with G4.

Integrating QIAseq® kits for DNA and RNA library preparation with G4.

Integrating Agilent® SureSelect Target Enrichment Reagents for RNA sequencing on G4.

Integrating Bio-Rad Laboratories to integrate its high-performance SEQuoia library prep kits for RNA-Seq with G4.

Integrating IDT xGen™ NGS Library Preparation Kits for both DNA and RNA sample prep with G4.

Integrating Watchmaker® DNA Library Prep Kits with Fragmentation with G4.

Integrating Parse Biosciences Evercode™ Whole Transcriptome products for single cell RNA-Seq with G4.

Takara

Integrating Takara Bio single cell RNA-Seq kits, including SMART-Seq and other NGS technologies, with G4.

Integrating the QuantaBio high-quality sparQ library prep kits for RNA-Seq with G4.

Validating Tecan MagicPrep™ NGS system to create sequencing-ready libraries for G4.

Integrating Claret Bioscience SRSLY® NGS library prep kit for degraded DNA with G4.

Integrating Paragon Genomics CleanPlex® targeted NGS amplicon panels with G4.

Integrating Fluent Biosciences PIPseq™ Single Cell RNA Kits with G4.

Integrating Phase Genomics OncoTerra™ Platform with G4.

Integrating Cantata Bio® proximity ligation-based NGS library prep kits with the G4.

Integrating QuantSeq®, CORALL®, and LUTHOR® library preparation kits for RNA sequencing on G4.

Integrating the Twist® NGS Target Enrichment Solutions for the G4 Sequencing Platform.

Integrating Olink® Explore high-throughput proteomics platform with G4 (in development).

Interested in integrating a library prep workflow not listed here? No problem! Contact us for more information.

Sequencing on the G4

G4 has been thoughtfully designed with an intuitive user interface and easy to use consumables to enable anyone to load and run a broad range of applications on the platform.

Bioinformatics & Cloud Storage Partners

Integrating NVIDIA Clara Parabricks for secondary analysis of NGS DNA and RNA data generated by G4.

Integrating the Terra platform—developed by the Broad Institute of MIT and Harvard, Microsoft, and Verily—for secondary and tertiary data analysis, storage, and sharing of G4-generated data.

Download Application Note in Partnership With Roche

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Download the Single Cell Application Note

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Download RNA-Seq Application Note

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Download NGS Application Note in Partnership With QIAGEN

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Download Application Note

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Download RNA Sequencing Application Note in Partnership With Bio-rad

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Download Quantabio Transcriptome Application Note

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Download Library Preparation Poster in Partnership With Watchmaker Genomics

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Download Parse Biosciences Application Note

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Download Takara Bio Application Note

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Download Poster in Partnership With Tecan

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Download Application Note in Partnership With Claret Bioscience

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Download Application Note in Partnership With Paragon Biosciences

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Drew Spaventa

Drew founded Singular Genomics in 2016 serving as the CEO and Chairman. Drew is a serial entrepreneur and venture investor in the biotech industry and has been involved in the founding of several successful companies. Prior to Singular Genomics, Drew founded Truvian Sciences, a low volume blood testing technology aimed at making routine blood tests easier, less invasive, and more affordable. Drew was also involved in the founding of Aspen Neurosciences where he co-led the seed financing and helped assemble a world-class team to combat Parkinson’s Disease using a patient’s own stem cells. Drew was also a seed investor and held an operating role in Edico Genome which sold to Illumina in 2018.

Drew received an MBA from the Rady School of Management at the University of California, San Diego and a BA in Political Science and International Relations from the University of California, San Diego.

Max Reads Application Note