Applications
The G4 has been designed to deliver fast, flexible sequencing for a range of genomic applications. Explore the data and performance for your applications.
Unmatched Versatility Serving a Broad Range of Applications
3.2 Billion Reads
up to480 Gb
<24 Hour Run Times
1-4 Flow Cells
4-16 Lanes
Explore your Applications
RNA Sequencing
RNA sequencing (RNA-Seq) is used to assess differential gene expression profiles, detect novel transcripts, and characterize new splice variants or cell types. Explore how the reimagined chemistry and advanced engineering of the G4 can improve your RNA sequencing.
| F2 Flow Cell Samples / FC | F3 Flow Cell Samples / FC | Samples / Run |
|---|---|---|
| 4 | 8 | 32 |
(2 x 100 bp, 50M reads)
Single Cell RNA Sequencing
Single cell RNA sequencing (scRNA-Seq) has revolutionized basic and translational research in immunology, developmental biology and cancer by enabling the resolution of distinct cell populations within heterogeneous samples. Explore how the G4 can seamlessly integrate into your scRNA-Seq workflow and accelerate your results without sacrificing accuracy.
| F2 Flow Cell Samples / FC | F3 Flow Cell Samples / FC | Max Read Samples / FC | Samples / Run |
|---|---|---|---|
| 1 | 2 | 4 | 16 |
(28×91 configuration, 10,000 cells/sample and 20,000 reads/cell)
Whole Exome Sequencing
Whole exome sequencing (WES) is a next-generation sequencing method used to discover and assess genetic variations linked to rare or complex diseases. Learn how the G4 provides excellent variant-calling accuracy and unmatched speed and versatility to labs performing WES.
| F2 Flow Cell Samples / FC | F3 Flow Cell Samples / FC | Samples / Run |
|---|---|---|
| 6 | 13 | 52 |
(2 x 100 bp, 34Mb at 100x coverage)
Whole Genome Sequencing
Whole genome sequencing (WGS) is the process for analyzing the complete genetic makeup of an organism. Learn more about the suitability of the G4 for human whole genome sequencing in the WGS technical report.
| F2 Flow Cell Samples / FC | F3 Flow Cell Samples / FC | Samples / Run |
|---|---|---|
| — | 1 | 4 |
(2 x 150 bp, 3Gb at 30x coverage)
Metagenome Sequencing
Metagenomic next-generation sequencing (mNGS), also known as shotgun sequencing, is considered a “hypothesis-free” approach that enables researchers to identify potential pathogens in a heterogeneous mixture of microbes, through a sensitive and unbiased method. Explore how G4 performance and run flexibility are accelerating research for labs running metagenome sequencing.
| F2 Flow Cell Samples / FC | F3 Flow Cell Samples / FC | Samples / Run |
|---|---|---|
| 20 | 40 | 160 |
(2 x 150 bp, 3Gb at 30x coverage)
Sample Cost Comparison Tool
Compare flow cell, cost, and run time efficiency against the NextSeq 2000 for your application.
Overview
Click on the flow cell configurations for more read details. Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000.
Flow Cell Configuration
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- Unused flow cell space
- Used flow cell space
G4
G4
1 F2 Flow Cell
200M Reads
G4
1 F3 Flow Cell
400M Reads
G4
1 F2 + 1 F3 Flow Cell
600M Reads
G4
2 F3 Flow Cells
800M Reads
G4
1 F2 + 2 F3 Flow Cells
1B Reads
G4
3 F3 Flow Cells
1.2B Reads
G4
1 F2 + 3 F3 Flow Cells
1.4B Reads
G4
4 F3 Flow Cells
1.6B Reads
- Flow Cell 1
- Flow Cell 2
- Flow Cell 3
Reads
Delivered
NextSeq 2000
NextSeq 2000
100M reads
NextSeq 2000
400M reads
NextSeq 2000
1.2B reads
Shotgun Metagenomics
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Transcriptomes
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Exomes
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Small RNA
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Single Cell
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Overview
Click on the flow cell configurations for more read details. Select your application and number of samples to compare flow cell, cost, and run time efficiency against the NextSeq 2000.
Flow Cell Configuration
- 1
- 2
- 3
- 4
- 5
- 6
- 7
- 8
- Unused flow cell space
- Used flow cell space
G4
G4
1 F2 Flow Cell
200M Reads
G4
1 F3 Flow Cell
400M Reads
G4
1 F2 + 1 F3 Flow Cell
600M Reads
G4
2 F3 Flow Cells
800M Reads
G4
1 F2 + 2 F3 Flow Cells
1B Reads
G4
3 F3 Flow Cells
1.2B Reads
G4
1 F2 + 3 F3 Flow Cells
1.4B Reads
G4
4 F3 Flow Cells
1.6B Reads
- Flow Cell 1
- Flow Cell 2
- Flow Cell 3
Reads
Delivered
NextSeq 2000
NextSeq 2000
100M reads
NextSeq 2000
400M reads
NextSeq 2000
1.2B reads
Shotgun Metagenomics
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the leading benchtop sequencer. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Transcriptomes
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the leading benchtop sequencer. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Exomes
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the leading benchtop sequencer. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Small RNA
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the leading benchtop sequencer. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Single Cell
Select your application and number of samples to compare flow cell, cost, and run time efficiency against the leading benchtop sequencer. Click on the flow cell configurations for more information.
- Unused flow cell space
- Used flow cell space
G4
NextSeq 2000
Innovation with Intention
Featuring novel, high-performance chemistry and advanced engineering, the G4 Sequencing Platform has been optimized to deliver speed, power, unprecedented flexibility, and accuracy.